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A Possible New Use for Ketamine? Depression and Aggression

A Possible New Use for Ketamine? Depression and Aggression

Depressive Symptoms Associated With Aggression Violence is not usually considered to be related to depression, yet findings suggest an association between violent behavior and depression or depressive symptoms in many different disorders. A Swedish study compared the criminal records of 47,158 depressed individuals with the records of 898,454 people with no history of depression matched […]

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Low-Dose Ketamine In Treating Depression: An Outsider’s Perception

Low-Dose Ketamine In Treating Depression: An Outsider’s Perception

A Very Moving and Well Written Account from a Healthcare Professional and Parent As both a healthcare professional and a parent of a child who suffers from treatment resistant depression and anxiety, I have been quite attentive to the changes that arise in an individual after receiving low-dose ketamine. I thought it would be helpful […]

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Ketamine Featured in the Globe and Mail: Offers New Hope for Patients with Severe Depression

Ketamine Featured in the Globe and Mail: Offers New Hope for Patients with Severe Depression

WENCY LEUNG The Globe and Mail Published Thursday, Feb. 16, 2017 3:23PM EST Last updated Thursday, Feb. 16, 2017 5:18PM EST Inspired by promising research into ketamine’s therapeutic effects, people are swapping strategies online on how to use the drug to ease their despair. Could ‘Special K’ be a panacea for depression? Wency Leung reports […]

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Ketamine Featured on DrugTargetReview.com

Ketamine Featured on DrugTargetReview.com

How Ketamine Could Cure Depression The major excitatory neurotransmitter in the central and peripheral nervous system, glutamic acid, has been known for more than 50 years to produce its actions through various ionotropic channels (NMDA and AMPA) and G-coupled metabotropic receptors (mGluR 1 to 5). The glutamate-sensitive ion channels comprise multiple protein subunits and are subject […]

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When Is Depression ‘Treatment Resistant’?

When Is Depression ‘Treatment Resistant’?

When should you, the prescriber, conclude that your patient with depression is “treatment resistant,” and thereby eligible for alternative non-pharmacological interventions—such as vagus nerve stimulation (VNS), electroconvulsive therapy (ECT), or transcranial magnetic stimulation (TMS)? There are multiple ways that the failure to agree on a standardized definition of treatment-resistant depression (TRD) impacts the clinical care […]