Posted by
How COVID-19 Compares With Other Illnesses

How COVID-19 Compares With Other Illnesses

What does being sick with COVID-19 look like compared with a cold or the flu? Check what types of symptoms show up for each illness and how often in the chart below.  NOTE: If you have not been to a country or area with an outbreak of COVID-19 or have not had contact with someone who […]

Posted by
Disturbed, A Reason to Fight

Disturbed, A Reason to Fight

Our world is plagued by an epidemic. By a disease that shows no mercy. The demons known as addiction and depression are very real. And they have claimed far too many of those we love, far soonerthan they should have left us. Those still with us are fighting a battle they wage every day oftheir lives keeping those demons at […]

Posted by
Unlocking the Mysteries of the Glutamate System

Unlocking the Mysteries of the Glutamate System

Ketamine, Similar Compounds Emerging as Mood Disorder Treatments Sanjay J. Mathew, MD, vice chair for research at Baylor College of Medicine and staff physician at the Michael E. Debakey VA Medical Center in Houston, Texas, has long been interested in the brain’s glutamate system and how it could be manipulated with substances such as ketamine to […]

Posted by

Trial of SAGE-217 in Patients with Major Depressive Disorder

Handan Gunduz-Bruce, M.D.,  Christopher Silber, M.D.,  Inder Kaul, M.D.,  Anthony J. Rothschild, M.D.,  Robert Riesenberg, M.D.,  Abdul J. Sankoh, Ph.D.,  Haihong Li, Ph.D.,  Robert Lasser, M.D.,  Charles F. Zorumski, M.D.,  David R. Rubinow, M.D.,  Steven M. Paul, M.D.,  Jeffrey Jonas, M.D.,  et al. Abstract BACKGROUND Altered neurotransmission of γ-aminobutyric acid (GABA) has been implicated in […]

Posted by
Antidepressant Adherence Linked to Increased Survival in Patients With Cancer, Study Finds

Antidepressant Adherence Linked to Increased Survival in Patients With Cancer, Study Finds

A study published this week in Depression & Anxiety suggests that among patients with cancer who are prescribed antidepressants, those who take the medication may live longer than those who are non-adherent. Patients with cancer are known to have higher rates of depression than the general public—a factor that may reduce adherence to cancer treatment and increase their […]

Posted by
How Pharmacogenomics Can Help Patients with Treatment-Resistant Depression

How Pharmacogenomics Can Help Patients with Treatment-Resistant Depression

Treatment-resistant depression can be a frustrating challenge for doctor and patient alike. The trial-and-error process of trying different medications and treatments to see what alleviates patients’ depression symptoms can feel like a “shot in the dark” approach. According to Ann McDonald, former editor of the Harvard Mental Health Letter, in her blog post on the Harvard […]

Posted by
Mild Depression Predictive of All-Cause Mortality After MI

Mild Depression Predictive of All-Cause Mortality After MI

Mild depression was a long-term independent predictor of death in patients after acute myocardial infarction (AMI), per cohort study data published in Heart, Lung and Circulation. Investigators conducted a 25-year follow-up of men who were recruited after AMI to participate in a randomized controlled trial in the 1980s. The initial trial investigated the impact of high intensity exercise […]