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How Pharmacogenomics Can Help Patients with Treatment-Resistant Depression

How Pharmacogenomics Can Help Patients with Treatment-Resistant Depression

Treatment-resistant depression can be a frustrating challenge for doctor and patient alike. The trial-and-error process of trying different medications and treatments to see what alleviates patients’ depression symptoms can feel like a “shot in the dark” approach. According to Ann McDonald, former editor of the Harvard Mental Health Letter, in her blog post on the Harvard […]

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Precision Medicine:The Future is Coming Fast

Precision Medicine:The Future is Coming Fast

Promise of Precision Medicine in Psychiatry Nears Reality BARCELONA, Spain — Innovative approaches and widespread data sharing are essential in psychiatry to improve patient care and deliver on the long-held promise of precision medicine, a leading European expert says. In a plenary lecture delivered here at the 31st European College of Neuropsychopharmacology (ECNP) Congress, Marion […]

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The APA Brings Genetic Testing Under Fire, Genomind and Genesight Respond

On April 25th 2018 the American Psychiatric Association published the following criticism of genomic testing emphasizing their skepticism towards psychiatrists who are using genetic testing to make informed decisions about diagnosis and treatment. An abstract of their statement reads:       Evidence Does Not Support Commercial Rush Of DNA Tests Designed To Inform Decisions […]

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The Glutamate Hypothesis in Synaptic Connectivity

Glutamate neurotransmission is an active area of research in major depressive disorder (MDD).1 Much of this interest revolves around glutamate’s role in regulating synaptic connectivity, one of several pathways that may strengthen and initiate the formation of new synaptic connections.1 As research advances, a deeper understanding of MDD is within reach. Watch our video featuring Dr […]

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Sources of Parent-Offspring Resemblance for Major Depression

Sources of Parent-Offspring Resemblance for Major Depression

Question: How do effects of genetics and rearing each contribute to the transmission of risk for major depression from parents to children?   Findings: In this population register–based study of 2 269 552 offspring of intact, adoptive, not-lived-with father, stepfather, and triparental families from the general Swedish population, the effects of genes and rearing were […]